Structural and Functional MRI Techniques in Multiple Sclerosis Related Cognitive Dysfunction

Dessislava Iancheva¹, Anastasiya Trenova¹, Stefka Mantarova^1,2, Kiril Terziyski³

¹ Department of Neurology, Medical University of Plovdiv, Plovdiv, BulgariaStructural and Functional MRI Techniques in Multiple Sclerosis Related Cognitive Dysfunction
² Department of Neurology, Medical University of Plovdiv, Military Medical Academy, Plovdiv, BulgariaStructural and Functional MRI Techniques in Multiple Sclerosis Related Cognitive Dysfunction
³ Department of Pathophysiology, Medical University of Plovdiv, Plovdiv, Bulgaria

The Role of Antiobesity Agents in the Management of Polycystic Ovary Syndrome

Panagiotis Chatzis¹, Konstantinos Tziomalos², Georgios C. Pratilas¹, Vasileios Makris¹, Alexandros Sotiriadis¹, Konstantinos Dinas¹

¹ Second Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece
² First Propedeutic Department of Internal Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, GreeceThe Role of Antiobesity Agents in the Management of Polycystic Ovary Syndrome

Mutations Associated with Imatinib Mesylate Resistance - Review

Alexandar J. Linev^1,2, Hristo J. Ivanov¹, Ivan G. Zhelyazkov², Hristina Ivanova³, Veselina S.Goranova-Marinova³, Vili K. Stoyanova^1,2

¹ Department of Pediatrics and Medical Genetics, Medical University of Plovdiv, Plovdiv, Bulgaria
² Department of Medical Genetics, St George University Hospital, Medical University of Plovdiv, Plovdiv, Bulgaria
³ First Department of Internal Diseases, Department of Hematology, Medical University of Plovdiv, Plovdiv, BulgariaMutations Associated with Imatinib Mesylate Resistance - Review

Oral Lichen Planus – Known and Unknown: a Review

Maria Z. Mutafchieva¹, Milena N. Draganova-Filipova^2,3, Plamen I. Zagorchev⁴, George T. Tomov¹

¹ Department of Periodontology and Oral Diseases, Faculty of Dental Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
² Department of Medical Biology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
³ Technological Center of Emergency, Plovdiv, BulgariaOral Lichen Planus – Known and Unknown: a Review
⁴ Department of Medical Physics and Biophysics, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria

Stability of Frequent Exacerbator Phenotype in Patients with Chronic Obstructive Pulmonary Disease

Iliya Krachunov¹, Nikolay Kyuchukov¹, Zlatina Ivanova¹, Nikolay A. Yanev⁴, Petkana A. Hristova³, Plamen Pavlov¹, Pavlina Glogovska¹, Tsanya Popova², Yavor Y. Ivanov¹

¹ Clinic of Pneumonology and Phthisiatry, Medical University, Pleven, Bulgaria
² Department of Internal Diseases, Dr. Georgi Stranski University Hospital, Pleven, Bulgaria
³ Department of Social and Preventive Medicine, Medical Statistics, Pedagogy and Psychology, Medical University, Pleven, BulgariaStability of Frequent Exacerbator Phenotype in Patients with Chronic Obstructive Pulmonary Disease
⁴ Clinic of Pulmonology, St Sofi a University Hospital for Pulmonary Diseases, Sofi a, Bulgaria

Cortisol Correlates with Structural Magnetic Resonance Imaging Parameters in Middle Aged Bulgarian Patients with Metabolic Syndrome: A Pilot Study

Karamfi l M. Bahchevanov¹, Penka A. Atanassova¹, Kostadin A. Chompalov¹, Mitko D. Mitkov², Borislav I. Milev⁷, Dora D. Terzieva³, Valcho I. Naydenov¹, Vesselina S. Dosheva¹, Radka I. Masaldjieva⁴, Kichka G. Velkova⁵, Nikolai V. Sirakov⁵, Kristina P. Kilova⁶

¹ Department of Neurology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
² Second Department of Internal Diseases, Section of Endocrinology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv,
Bulgaria
³ Department of Clinical Laboratory, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria
⁴ Department of Healthcare Management, Faculty of Public Health, Medical University of Plovdiv, Plovdiv, BulgariaCortisol Correlates with Structural Magnetic Resonance Imaging Parameters in Middle Aged Bulgarian Patients with Metabolic Syndrome: A Pilot Study
⁵ Department of Diagnostic Imaging, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
⁶ Department of Medical Informatics, Biostatistics and E-learning, Faculty of Public Health, Medical University of Plovdiv, Plovdiv,
Bulgaria
⁷ Russev Independent Medical Laboratory, Plovdiv, Bulgaria

Neutrophil-to-Lymphocyte Ratio in Renal Cell Carcinoma Patients

Selahattin Çalışkan1, Mustafa Sungur¹, Selçuk Kaba², Emrah Özsoy², Orhan Koca², Metin İshak Öztürk²

¹ Department of Urology, Çorum Training and Research Hospital, Hitit University, Çorum, TurkeyNeutrophil-to-Lymphocyte Ratio in Renal Cell Carcinoma Patients
² Department of Urology, Haydarpaşa Numune Training and Research Hospital

Maternal Serum Concentrations of Corin, Endoglin, PP13, and sFlt-1 and their Changes with Advancement of Pregnancy and Correlation with Doppler of Uterine Arteries

Krasimira I. Chalova¹, Blagovest K. Pehlivanov², Iliya G. Amaliev¹, Georgi I. Amaliev¹, Ralitsa D. Raycheva³, Mariya V. Ivanovska⁴

¹ Department of Obstetrics and Gynaecology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
² Department of Midwifery Cares, Faculty of Public Health, Medical University of Plovdiv, Plovdiv, Bulgaria
³ Department of Social Medicine and Public Health, Faculty of Public HeMaternal Serum Concentrations of Corin, Endoglin, PP13, and sFlt-1 and their Changes with Advancement of Pregnancy and Correlation with Doppler of Uterine Arteriesalth, Medical University of Plovdiv, Plovdiv, Bulgaria
⁴ Department of Microbiology and Immunology, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria

Vascular Risk Factors in Bulgarian Volunteers in Middle Adulthood

Kostadin A. Chompalov¹, Penka A. Atanassova¹, Radka I. Massaldjieva², Karamfi l M. Bahchevanov¹, Borislav A. Milev⁴, Valcho A. Naydenov³, Veselina S. Dosheva¹, Mariya A. Semerdzhieva²

¹ Department of Neurology, Faculty of Medicine, St George University Hospital, Medical University of Plovdiv, Plovdiv, Bulgaria
² Department of Health Care Management, Faculty of Public Health, Medical University of Plovdiv, Plovdiv, Bulgaria
³ Clinic of Neurology, Faculty of Medicine, Kaspela University Hospital, Medical University of Plovdiv, Plovdiv, BulgariaVascular Risk Factors in Bulgarian Volunteers in Middle Adulthood
⁴ Rusev Medical Diagnostic Laboratory, Kaspela University Hospital, Plovdiv, Bulgaria

Antioxidant Activity of Dry Birch (Betula Pendula) Leaves Extract

Dimitar Penkov^1,3, Velichka Andonova¹, Delian Delev², Ilia Kostadinov², Margarita Kassarova^{1,3Antioxidant Activity of Dry Birch (Betula Pendula) Leaves Extract}

¹ Department of Pharmaceutical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, Plovdiv, Bulgaria
² Department of Pharmacology and Clinical Pharmacology, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
³ High-technological Center of Emergency Medicine, Plovdiv, Bulgaria

Formulation Studies of Solid Self-Emulsifying Drug Delivery System of Ivermectin

 Formulation Studies of Solid Self-Emulsifying Drug Delivery System of Ivermectin

Vipul P. Patel, Hardik A. Lakkad, Kalpesh Chhotalal Ashara

School of Pharmacy, RK University, Rajkot, Gujarat, India

Triterpenoid and Fatty Acid Contents from the Stem Bark of Cordia dichotoma (Forst f.)

Pankajkumar B. Nariya¹, Vinay J. Shukla², R. N. Acharya², Mukeshkumar B. Nariya³, Jayesh M. Dhalani³, Anilkumar S. Patel¹, Pratik A. Ambasana¹

¹ Department of Chemistry, Shree M. & N. Virani Science College (Autonomous), Rajkot, India
² IPGT&RA, Gujarat Ayurved University, Jamnagar, IndiaTriterpenoid and Fatty Acid Contents from the Stem Bark of Cordia dichotoma (Forst f.)
³ Department of Chemistry, School of Science, RK University, Rajkot, India

In Silico and in Vitro Studies of Fluorinated Chroman-2-Carboxilic Acid Derivatives as an Anti-tubercular Agent

Khushal M. Kapadiya¹, Yashwantsinh S. Jadeja^2, Avishek Banik³, Ranjan C. Khunt²

 In Silico and in Vitro Studies of Fluorinated Chroman-2-Carboxilic Acid Derivatives as an Anti-tubercular Agent

¹ Department of Chemistry, RK University, Rajkot, Gujarat, India
² Department of Chemistry, Saurashtra University, Rajkot, Gujarat, India
³ Department of Microbiology, RK University, Rajkot, Gujarat, India

Histological Gingival Assessment after Conventional and Laser Gingivectomy

Rada T. Kazakova¹, Georgi T. Tomov², Christo K. Kissov¹, Angelina P. Vlahova¹, Stefan Ch. Zlatev¹, Svitlana Y. Bachurska³

 Histological Gingival Assessment after Conventional and Laser Gingivectomy

¹ Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
² Department of Periodontology and Oral Mucosa Diseases, Oral Pathology Division, Faculty of Dental Medicine, Medical University
of Plovdiv, Plovdiv, Bulgaria
³ Department of Clinical Pathology, Medical University of Plovdiv, Plovdiv, Bulgaria

Subgingival Microbiota during Formation of Permanent Dentition

Nadezhda G. Mitova¹, Maya R. Rashkova¹, Hristina L. Popova², Anton S. Kozarov³

 Subgingival Microbiota during Formation of Permanent Dentition

¹ Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University of Sofia, Sofia, Bulgaria
² Department of Periodontology, Faculty of Dental Medicine, Medical University of Sofia, Sofia, Bulgaria
³ Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Medical University of Sofia, Sofia, Bulgaria

Accuracy of Different Apex Locators in Teeth with Simulated Apical Root Resorption: an In Vitro Study

Ganesh Ranganath Jadhav^1, Priya Mittal², Vishal Patil³, Prashant Kandekar⁴, Anish Kulkarni⁵, Siddharth Shinde⁶, Shibli Syed⁷, Saina Elahi⁸

¹ Department of Conservative Dentistry and Endodontics, Sinhgad Dental College & Hospital, Pune, India
² Private Practitioner, Pune, India
³ Department of Conservative Dentistry and Endodontics, Aditya Dental College, Beed, IndiaAccuracy of Different Apex Locators in Teeth with Simulated Apical Root Resorption: an In Vitro Study
⁴ Department of Oral and Maxillofacial Pathology, Ibn Sina National College for Medical Studies, Jeddah, India
⁵ Private Practitioner, Pune, India
⁶ Department of Orthodontics, BVDU Dental College and Hospital, Pune, India
⁷ Private Practitioner, Pune, India
⁸ Department of Periodontology, MA Rangoonwala Dental College, Pune

Semen Quality and Ferritin and Transferrin Seminal Levels

Gilmar Pereira Silva¹, Vítor Pereira Xavier Grangeiro², Fabiana PiraniSemen Quality and Ferritin and Transferrin Seminal Levels Carneiro¹

¹ Department of Medicine, University of Brasilia, Brazil
² Department of Medicine, Faculty of Medical Sciences, João Pessoa, Paraíba, Brazil 

Neoadjuvant and Adjuvant Treatment with Denosumab in Aggressive Giant-cell Tumor of Bone in the Proximal Fibula: a Case Report

Violeta V. Marinova¹, Svetoslav A. Slavchev², Kircho D. Patrikov², Petya M. Tsenova1, Georgi P. Georgiev³

 Neoadjuvant and Adjuvant Treatment with Denosumab in Aggressive Giant-cell Tumor of Bone in the Proximal Fibula: a Case Report

¹ Department of Hematology and Medical Oncology, St Ivan Rilski University Hospital, Medical University of Sofia, Sofia, Bulgaria
² Department of Orthopedics and Traumatology, Prof. Boycho Boychev University Hospital of Orthopedics, Medical University of
Sofia, Sofia, Bulgaria
³ Department of Orthopedics and Traumatology, Queen Giovanna University Hospital - ISUL, Medical University of Sofia, Sofia, Bulgaria

Anorectal Melanoma - a Histopathological Case Report and a Review of the Literature

Ina Kobakova¹, George Stoyanov², HriAnorectal Melanoma - a Histopathological Case Report and a Review of the Literaturesto Popov², Snezhana Spasova-Nyagulova², Nadezhda Stefanova², Lyuben Stoev², Nevena Yanulova²

¹ Clinic of General and Clinical Pathology, St. Marina University Hospital, Varna, Bulgaria
² Department of General and Clinical Pathology, Forensic Medicine and Deontology, Faculty of Medicine, Prof. Dr. Parashkev
Stoyanov Medical University, Varna, Bulgaria

Gaucher Disease Involving Virchow’s Lymph Node: a Case Report

Dmitry A. Zinovkin¹, Md Zahidul Islam Pranjol^{2Gaucher Disease Involving Virchow’s Lymph Node: a Case Report}, Dmitry Kravchenko³, Olga Kravchenko4, Vadim Kudryashov⁴

¹ Department of Pathology, Gomel State Medical University, Gomel, Belarus
² William Harvey Research Institute, Barts & The London School of Medicine & Dentistry, Queen Mary University of London,
London, England
³ Republican Research Center for Radiation Medicine and Human Ecology, Gomel, Belarus
⁴ Regional Clinical Oncological Dispensary, Gomel, Belarus